혈액응고 메모


혈액응고 메모



응고 개요




Phases of Hemostasis





Platelet 의 조혈 과정




혈액 응고의 3가지 system





Role of platelet in Hemostasis




GpIIb/IIIa recepter




vWF-GpIb receptor





Glanzmann's thrombosthenia
Bernard Soulier syndrome

  - ADP, Collagen, Epi 는 혈소판을 활성화 시켜, GpIIb/IIIa 를 ligand receptive state 로 만든다.
  - Ristocetin 은 vWF 를 활성화 시킨다.





Platelet 의 function, vWF





Coagulation pathway





Physiological cascade vs. Classical cascade
--> Intrinsic pathway, Extrinsic pathway, Common pathway





Anticoagulation system






Inherited Thrombophilia






끝.
2018. 10. 29 - SJH


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